Diabetes leads to markedly accelerated rates of many associated macrovascular
complications like hypertension and atherosclerosis, and microvascular complications like
nephropathy and retinopathy. High glucose, the hallmark of diabetes, drives changes in
vascular and inflammatory cells that promote the development of these complications.
Understanding the molecular processes involved in the development of diabetes and its
debilitating complications can lead to much needed newer clinical therapies. Recently, long …