Serum levels of interleukin-8 in alcoholic liver disease: relationship with disease stage, biochemical parameters and survival

YS Huang, CY Chan, JC Wu, CH Pai, Y Chao… - Journal of …, 1996 - Elsevier
Backgrounds/Aims: Interleukin-8 (IL-8), a cytokine produced by a host of cells, including
monocytes macrophages, Kuppfer cells and hepatocytes, can activate neutrophils.
Peripheral neutrophilia and liver neutrophil infiltration are frequently noted in patients with
alcoholic liver disease. However, the relationship between IL-8 and different stages of
alcoholic liver disease is uncertain. The aim of this study is to determine if a correlation
exists between circulating Il-8 levels and biochemical and histological parameters and …