Background: There is evidence that amyotrophic lateral sclerosis (ALS), also known as
motor neuron disease (MND), is more common in men than in women and that gender
influences the clinical features of the disease. The causes of this are unknown. Objective:
This review examines the gender differences that are found in ALS and postulates reasons
for these differences. Methods: A literature review of PubMed (with no date limits) was
performed to find information about gender differences in the incidence, prevalence, and …