Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system

B Lassègue, A San Martín, KK Griendling - Circulation research, 2012 - Am Heart Assoc
Circulation research, 2012Am Heart Assoc
atherosclerosis, hypertension, cardiac hypertrophy and remodeling, angiogenesis and
collateral formation, stroke, and heart failure. In this review, we discuss in detail the
biochemistry of Nox enzymes expressed in the cardiovascular system (Nox1, 2, 4, and 5),
their roles in cardiovascular cell biology, and their contributions to disease development.
atherosclerosis, hypertension, cardiac hypertrophy and remodeling, angiogenesis and collateral formation, stroke, and heart failure. In this review, we discuss in detail the biochemistry of Nox enzymes expressed in the cardiovascular system (Nox1, 2, 4, and 5), their roles in cardiovascular cell biology, and their contributions to disease development.
Am Heart Assoc