Human effector/initiator gene sets that regulate myometrial contractility during term and preterm labor
CP Weiner, CW Mason, Y Dong, IA Buhimschi… - American journal of …, 2010 - Elsevier
OBJECTIVE: Distinct processes govern transition from quiescence to activation during term
(TL) and preterm labor (PTL). We sought gene sets that are responsible for TL and PTL,
along with the effector genes that are necessary for labor independent of gestation and
underlying trigger. STUDY DESIGN: Expression was analyzed in term and preterm with or
without labor (n= 6 subjects/group). Gene sets were generated with logic operations.
RESULTS: Thirty-four genes were expressed similarly in PTL/TL but were absent from …
(TL) and preterm labor (PTL). We sought gene sets that are responsible for TL and PTL,
along with the effector genes that are necessary for labor independent of gestation and
underlying trigger. STUDY DESIGN: Expression was analyzed in term and preterm with or
without labor (n= 6 subjects/group). Gene sets were generated with logic operations.
RESULTS: Thirty-four genes were expressed similarly in PTL/TL but were absent from …