Gastrointestinal manifestations of cystic fibrosis

T Kelly, J Buxbaum - Digestive diseases and sciences, 2015 - Springer
Digestive diseases and sciences, 2015Springer
Gastrointestinal symptoms of cystic fibrosis are the most important non-pulmonary
manifestations of this genetic illness. Pancreatic manifestations include acute and chronic
pancreatitis as well as pancreas insufficiency resulting in malnutrition. Complications in the
gastrointestinal lumen are diverse and include distal intestinal obstruction syndrome (DIOS),
meconium ileus, intussusception, and constipation; biliary tract complications include focal
biliary cirrhosis and cholangiectasis. The common pathophysiology is the inspissation of …
Abstract
Gastrointestinal symptoms of cystic fibrosis are the most important non-pulmonary manifestations of this genetic illness. Pancreatic manifestations include acute and chronic pancreatitis as well as pancreas insufficiency resulting in malnutrition. Complications in the gastrointestinal lumen are diverse and include distal intestinal obstruction syndrome (DIOS), meconium ileus, intussusception, and constipation; biliary tract complications include focal biliary cirrhosis and cholangiectasis. The common pathophysiology is the inspissation of secretions in the hollow structures of the gastrointestinal tract. Improved survival of CF patients mandates that the adult gastroenterologist be aware of the presentation and treatment of pancreatic, luminal, and hepatobiliary CF complications.
Springer