[HTML][HTML] Dysregulation of type I interferon responses in COVID-19

D Acharya, GQ Liu, MU Gack - Nature Reviews Immunology, 2020 - nature.com
Nature Reviews Immunology, 2020nature.com
Infection with SARS-CoV-2 can lead to excessive production of pro-inflammatory cytokines,
but the production of type I interferons, which are key antiviral mediators, is reportedly
blunted. Here, we discuss how imbalanced interferon responses may contribute to the
pathology of COVID-19.
Infection with SARS-CoV-2 can lead to excessive production of pro-inflammatory cytokines, but the production of type I interferons, which are key antiviral mediators, is reportedly blunted. Here, we discuss how imbalanced interferon responses may contribute to the pathology of COVID-19.
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