[HTML][HTML] The potential role of Th17 immune responses in coronavirus immunopathology and vaccine-induced immune enhancement

PJ Hotez, ME Bottazzi, DB Corry - Microbes and infection, 2020 - Elsevier
Increasing evidence points to host Th17 inflammatory responses as contributing to the
severe lung pathology and mortality of lower respiratory tract infections from coronaviruses.
This includes host inflammatory and cytokine responses to COVID-19 caused by the SARS-
2 coronavirus (SARS CoV2). From studies conducted in laboratory animals, there are
additional concerns about immune enhancement and the role of potential host
immunopathology resulting from experimental human COVID-19 vaccines. Here we …