Effect of clonidine in obstructive sleep Apnea1. 2

FG Issa - American Review of Respiratory Disease, 1992 - atsjournals.org
FG Issa
American Review of Respiratory Disease, 1992atsjournals.org
The current treatment of choice for obstructive sleep apnea is continuous positive airway
pressure. However, not all patients tolerate this form of therapy. We eveluated the effect of
clonldlne hydrochloride, an a,-adrenerglc agonist with REM-suppressant activity, In eight
male patients with obstructive sleep apnea. In each patient, sleep-stsge distribution and
breathing pattern
Summary
The current treatment of choice for obstructive sleep apnea is continuous positive airway pressure. However, not all patients tolerate this form of therapy. We eveluated the effect of clonldlne hydrochloride, an a,-adrenerglc agonist with REM-suppressant activity, In eight male patients with obstructive sleep apnea. In each patient, sleep-stsge distribution and breathing pattern
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