[PDF][PDF] Germinal center selection and the antibody response to influenza

GD Victora, PC Wilson - Cell, 2015 - cell.com
Cell, 2015cell.com
Germinal Center Selection and the Antibody Response to Influenza Page 1 Leading Edge
Minireview Germinal Center Selection and the Antibody Response to Influenza Gabriel D.
Victora1,* and Patrick C. Wilson2,* 1Whitehead Institute for Biomedical Research, Cambridge,
MA 02142, USA 2Department of Medicine, Section of Rheumatology, The Committee on
Immunology, The Knapp Center for Lupus and Immunology Research, The University of
Chicago, Chicago, IL 60637, USA *Correspondence: victora@wi.mit.edu (GDV) …
In this Minireview, we discuss basic aspects of germinal center biology in the context of immunity to influenza infection and speculate on how the simultaneous evolutionary races of virus and antibody may impact our efforts to design a universal influenza vaccine.
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