Presence of tumor necrosis factor alpha and interleukin-6 in renal mesangial cells of lupus nephritis patients

D Malide, P Russo, M Bendayan - Human pathology, 1995 - Elsevier
Tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6) antigenic sites were shown
within the resident glomerular mesangial cells of lupus nephritis patients applying the
colloidal gold immunocytochemical approach at the electron microscopic level. Using
specific polyclonal antibodies against human recombinant (hr) TNFα and hrIL-6 in
conjunction with the protein A-gold complex, TNFα and IL-6 were shown in the mesangial
cells, being particularly associated with the membranes of the rough endoplasmic reticulum …