Trained immunity by HSCs

L Bird - Nature Reviews Immunology, 2020 - nature.com
L Bird
Nature Reviews Immunology, 2020nature.com
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New research suggests that haematopoietic stem cells (HSCs) can contribute to trained immunity. Stimulation with lipopolysaccharide establishes long-lasting epigenetic changes in HSCs that confer improved responsiveness to secondary stimulation.
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