Colocalization of GABAA and NMDA receptors within the dorsal motor nucleus of the vagus nerve (DMV) of the rat

DL Broussard, H Li, SM Altschuler - Brain research, 1997 - Elsevier
DL Broussard, H Li, SM Altschuler
Brain research, 1997Elsevier
Changes in gastric motor activity are observed in response to glutamate and GABA in the
DMV. We investigated the expression of GABAA and NMDA receptors within DMV neurons
projecting to the stomach using pseudorabies virus (PRV). PRV immunoreactive (PRV-IR)
cells expressing GABAA α 1-IR, also expressed NMDAR1 suggesting that NMDA and
GABAA receptors are colocalized. These results provide a neuroanatomical basis for these
receptors jointly playing a role in gastric motor functions.
Changes in gastric motor activity are observed in response to glutamate and GABA in the DMV. We investigated the expression of GABAA and NMDA receptors within DMV neurons projecting to the stomach using pseudorabies virus (PRV). PRV immunoreactive (PRV-IR) cells expressing GABAA α 1-IR, also expressed NMDAR1 suggesting that NMDA and GABAA receptors are colocalized. These results provide a neuroanatomical basis for these receptors jointly playing a role in gastric motor functions.
Elsevier