[HTML][HTML] The saccharomyces cerevisiae lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme*♦

GS Han, WI Wu, GM Carman - Journal of Biological Chemistry, 2006 - ASBMB
Mg 2+-dependent phosphatidate (PA) phosphatase (3-sn-phosphatidate phosphohydrolase,
EC 3.1. 3.4) catalyzes the dephosphorylation of PA to yield diacylglycerol and P i. In this
work, we identified the Saccharomyces cerevisiae PAH1 (previously known as SMP2) gene
that encodes Mg 2+-dependent PA phosphatase using amino acid sequence information
derived from a purified preparation of the enzyme (Lin, Y.-P., and Carman, GM (1989) J. Biol.
Chem. 264, 8641–8645). Overexpression of PAH1 in S. cerevisiae directed elevated levels …