[HTML][HTML] Functional compensation for adipose differentiation-related protein (ADFP) by Tip47 in an ADFP null embryonic cell line
C Sztalryd, M Bell, X Lu, P Mertz… - Journal of Biological …, 2006 - ASBMB
Ectopic accumulation of lipid droplets in non-adipose tissues correlates with the degree of
insulin resistance in these tissues. Emerging evidence indicates that lipid droplets are
specialized organelles that participate in lipid metabolism and intracellular trafficking. These
properties are thought to derive from the lipid droplet-associated PAT protein family
(perilipin, ADFP, and Tip47). The functions of the ubiquitously distributed adipose
differentiation-related protein (ADFP) and Tip47 remain unknown. To evaluate the roles of …
insulin resistance in these tissues. Emerging evidence indicates that lipid droplets are
specialized organelles that participate in lipid metabolism and intracellular trafficking. These
properties are thought to derive from the lipid droplet-associated PAT protein family
(perilipin, ADFP, and Tip47). The functions of the ubiquitously distributed adipose
differentiation-related protein (ADFP) and Tip47 remain unknown. To evaluate the roles of …