A battery of motor tests in a neonatal mouse model of cerebral palsy

DN Feather-Schussler, TS Ferguson - JoVE (Journal of Visualized …, 2016 - jove.com
As the sheer number of transgenic mice strains grow and rodent models of pediatric disease
increase, there is an expanding need for a comprehensive, standardized battery of neonatal
mouse motor tests. These tests can validate injury or disease models, determine treatment
efficacy and/or assess motor behaviors in new transgenic strains. This paper presents a
series of neonatal motor tests to evaluate general motor function, including ambulation,
hindlimb foot angle, surface righting, negative geotaxis, front-and hindlimb suspension …