On the alert for cytokine storm: immunopathology in COVID‐19

LA Henderson, SW Canna, GS Schulert… - Arthritis & …, 2020 - Wiley Online Library
LA Henderson, SW Canna, GS Schulert, S Volpi, PY Lee, KF Kernan, R Caricchio
Arthritis & rheumatology, 2020Wiley Online Library
Poor outcomes in COVID‐19 correlate with clinical and laboratory features of cytokine storm
syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy
may prevent immunopathology and could help conserve limited health care resources.
While studies are ongoing, extrapolating from clinical experience in cytokine storm
syndromes may benefit the multidisciplinary teams caring for patients with severe COVID‐
19.
Poor outcomes in COVID‐19 correlate with clinical and laboratory features of cytokine storm syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy may prevent immunopathology and could help conserve limited health care resources. While studies are ongoing, extrapolating from clinical experience in cytokine storm syndromes may benefit the multidisciplinary teams caring for patients with severe COVID‐19.
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