[PDF][PDF] Cut your losses: spastin mediates branch-specific axon loss

H Meltzer, O Schuldiner - Neuron, 2016 - cell.com
H Meltzer, O Schuldiner
Neuron, 2016cell.com
In this issue of Neuron, Brill et al.(2016) demonstrate that, during synapse elimination in the
developing neuromuscular junction, branch-specific microtubule destabilization results in
arrested axonal transport and induces axon branch loss. This process is mediated in part by
the neurodegeneration-associated, microtubule-severing protein spastin.
In this issue of Neuron, Brill et al. (2016) demonstrate that, during synapse elimination in the developing neuromuscular junction, branch-specific microtubule destabilization results in arrested axonal transport and induces axon branch loss. This process is mediated in part by the neurodegeneration-associated, microtubule-severing protein spastin.
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