Microcolony survival assay for cells of mouse intestinal mucosa exposed to radiation
HR Withers, MM Elkind - … Journal of Radiation Biology and Related …, 1970 - Taylor & Francis
HR Withers, MM Elkind
International Journal of Radiation Biology and Related Studies in …, 1970•Taylor & FrancisA microcolony technique for assaying the survival of small proportions of the clonogenic
cells of the mucosa of the small intestine of mice is described. The radiosensitivity of
intestinal crypt cells measured by the technique is the same as that measured by a
macrocolony method. However, the microcolony technique has the special advantage of
being useful for assaying cell survival after whole-body radiation.
cells of the mucosa of the small intestine of mice is described. The radiosensitivity of
intestinal crypt cells measured by the technique is the same as that measured by a
macrocolony method. However, the microcolony technique has the special advantage of
being useful for assaying cell survival after whole-body radiation.
Summary
A microcolony technique for assaying the survival of small proportions of the clonogenic cells of the mucosa of the small intestine of mice is described. The radiosensitivity of intestinal crypt cells measured by the technique is the same as that measured by a macrocolony method. However, the microcolony technique has the special advantage of being useful for assaying cell survival after whole-body radiation.
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