Evaluation of the possible protective role of naringenin on gentamicin-induced ototoxicity: A preliminary study
İ Koçak, S Sarac, E Aydogan, E Şentürk… - International journal of …, 2017 - Elsevier
Objectives The purpose of this study is to evaluate the possible protective role of naringenin
in gentamicin-induced ototoxicity through an audiological, biochemical and
histopathological evaluation. Methods This study was conducted on 32 adult male rats that
were randomized into 4 groups (control, gentamicin, naringenin+ gentamicin, and
naringenin). Naringenin was given to the rats via oral gavage in a dose of 50 mg/kg/day
during the 14 day study period. Gentamicin was given by the intraperitoneal route in a dose …
in gentamicin-induced ototoxicity through an audiological, biochemical and
histopathological evaluation. Methods This study was conducted on 32 adult male rats that
were randomized into 4 groups (control, gentamicin, naringenin+ gentamicin, and
naringenin). Naringenin was given to the rats via oral gavage in a dose of 50 mg/kg/day
during the 14 day study period. Gentamicin was given by the intraperitoneal route in a dose …