Importance Individuals genetically predisposed to pancreatic cancer may benefit from early
detection. Genes that predispose to pancreatic cancer and the risks of pancreatic cancer
associated with mutations in these genes are not well defined. Objective To determine
whether inherited germline mutations in cancer predisposition genes are associated with
increased risks of pancreatic cancer. Design, Setting, and Participants Case-control analysis
to identify pancreatic cancer predisposition genes; longitudinal analysis of patients with …