Effects of fructose vs glucose on regional cerebral blood flow in brain regions involved with appetite and reward pathways

KA Page, O Chan, J Arora, R Belfort-DeAguiar… - Jama, 2013 - jamanetwork.com
Importance Increases in fructose consumption have paralleled the increasing prevalence of
obesity, and high-fructose diets are thought to promote weight gain and insulin resistance.
Fructose ingestion produces smaller increases in circulating satiety hormones compared
with glucose ingestion, and central administration of fructose provokes feeding in rodents,
whereas centrally administered glucose promotes satiety. Objective To study
neurophysiological factors that might underlie associations between fructose consumption …