Increased serum levels of interleukin 33 in patients with atopic dermatitis

R Tamagawa-Mineoka, Y Okuzawa, K Masuda… - Journal of the American …, 2014 - Elsevier
Background Interleukin (IL)-33 is a new member of the IL-1 cytokine family and a promoter of
T helper type 2 (Th2) inflammation. IL-33 may be involved in the pathogenesis of atopic
dermatitis (AD), but its relationship with disease severity, laboratory markers, and eruption
types in patients with AD are unclear. Objective The aim of this study was to quantify serum
IL-33 levels in patients with AD and to examine relationships with disease severity,
laboratory markers, and eruption types. Methods Serum IL-33 was measured by enzyme …