[PDF][PDF] The mitochondrial pyruvate carrier: has it been unearthed at last?

AP Halestrap - Cell metabolism, 2012 - cell.com
Cell metabolism, 2012cell.com
The mitochondrial pyruvate carrier (MPC) is essential for several major pathways of
carbohydrate, fat, and amino acid metabolism, yet its molecular identity has remained
elusive. Two recent papers in Science (Herzig et al., 2012; Bricker et al., 2012) implicate
three newly identified inner mitochondrial membrane proteins as MPC components.
The mitochondrial pyruvate carrier (MPC) is essential for several major pathways of carbohydrate, fat, and amino acid metabolism, yet its molecular identity has remained elusive. Two recent papers in Science (Herzig et al., 2012; Bricker et al., 2012) implicate three newly identified inner mitochondrial membrane proteins as MPC components.
cell.com