[HTML][HTML] Vascular regeneration in adult mouse cochlea stimulated by VEGF-A165 and driven by NG2-derived cells ex vivo

X Wang, J Zhang, G Li, N Sai, J Han, Z Hou… - Hearing research, 2019 - Elsevier
Can damaged or degenerated vessels be regenerated in the ear? The question is clinically
important, as disruption of cochlear blood flow is seen in a wide variety of hearing disorders,
including in loud sound-induced hearing loss (endothelial injury), ageing-related hearing
loss (lost vascular density), and genetic hearing loss (eg, Norrie disease: strial
avascularization). Progression in cochlear blood flow (CBF) pathology can parallel
progression in hair cell and hearing loss. However, neither new vessel growth in the ear, nor …