[PDF][PDF] Pericytes: blood-brain barrier safeguards against neurodegeneration?
A Quaegebeur, I Segura, P Carmeliet - Neuron, 2010 - cell.com
A Quaegebeur, I Segura, P Carmeliet
Neuron, 2010•cell.comThe role of pericytes in the control of blood-brain barrier (BBB) integrity has remained
enigmatic. In this issue, Bell et al. and two concurrent studies highlight that pericyte loss
causes BBB breakdown and hypoperfusion. Remarkably, these vascular changes precede
neurodegeneration and cognitive defects in old age.
enigmatic. In this issue, Bell et al. and two concurrent studies highlight that pericyte loss
causes BBB breakdown and hypoperfusion. Remarkably, these vascular changes precede
neurodegeneration and cognitive defects in old age.
The role of pericytes in the control of blood-brain barrier (BBB) integrity has remained enigmatic. In this issue, Bell et al. and two concurrent studies highlight that pericyte loss causes BBB breakdown and hypoperfusion. Remarkably, these vascular changes precede neurodegeneration and cognitive defects in old age.
cell.com