[HTML][HTML] G0/G1 switch gene 2 regulates cardiac lipolysis

C Heier, FPW Radner, T Moustafa, R Schreiber… - Journal of Biological …, 2015 - ASBMB
The anabolism and catabolism of myocardial triacylglycerol (TAG) stores are important
processes for normal cardiac function. TAG synthesis detoxifies and stockpiles fatty acids to
prevent lipotoxicity, whereas TAG hydrolysis (lipolysis) remobilizes fatty acids from
endogenous storage pools as energy substrates, signaling molecules, or precursors for
complex lipids. This study focused on the role of G 0/G 1 switch 2 (G0S2) protein, which was
previously shown to inhibit the principal TAG hydrolase adipose triglyceride lipase (ATGL) …