Acute and chronic systemic corticosteroid–related complications in patients with severe asthma
P Lefebvre, MS Duh, MH Lafeuille, L Gozalo… - Journal of Allergy and …, 2015 - Elsevier
Background Many patients with severe asthma require maintenance treatment with systemic
corticosteroids (SCSs) to control daily symptoms and prevent serious acute exacerbations,
but chronic SCS use is associated with complications. Objective We sought to evaluate the
risk of SCS-related complications by SCS exposure and quantify the associated health care
costs and resource use in patients with severe asthma. Methods We performed a
longitudinal, open-cohort, observational study using health insurance claims data (1997 …
corticosteroids (SCSs) to control daily symptoms and prevent serious acute exacerbations,
but chronic SCS use is associated with complications. Objective We sought to evaluate the
risk of SCS-related complications by SCS exposure and quantify the associated health care
costs and resource use in patients with severe asthma. Methods We performed a
longitudinal, open-cohort, observational study using health insurance claims data (1997 …