Quercetine attenuates the gentamicin-induced ototoxicity in a rat model
M Sagit, F Korkmaz, SG Gürgen, R Gundogdu… - International Journal of …, 2015 - Elsevier
Objectives The aim of this study is to evaluate the protective role of quercetin in gentamicin-
induced ototoxicity through an auditory brainstem response (ABR) test and a
histopathological evaluation of the cochlea. Methods In this study, 48 female adult Sprague–
Dawley rats aged 20–22 weeks and weighing 200–250 g were used. An ABR test was
carried out on all rats prior to drug administration, after which, the rats were divided into four
groups of 12 animals each. Drug administration was gentamicin 120 mg/kg plus ethanol in …
induced ototoxicity through an auditory brainstem response (ABR) test and a
histopathological evaluation of the cochlea. Methods In this study, 48 female adult Sprague–
Dawley rats aged 20–22 weeks and weighing 200–250 g were used. An ABR test was
carried out on all rats prior to drug administration, after which, the rats were divided into four
groups of 12 animals each. Drug administration was gentamicin 120 mg/kg plus ethanol in …