Quercetin protects against hair cell loss in the zebrafish lateral line and guinea pig cochlea
Y Hirose, K Sugahara, E Kanagawa, Y Takemoto… - Hearing Research, 2016 - Elsevier
Eighteen supplement drugs were screened using hair cells to determine a protective effect
against the adverse effects of neomycin by using the zebrafish lateral line. The zebrafish
were administered the supplement drugs 1 h before neomycin exposure. One hour later,
animals were fixed in paraformaldehyde. Dose-response curves were generated to evaluate
the protective effect on hair cells. The screen identified 3 supplements (quercetin, catechin
and tannic acid). Three minutes after exposure to neomycin, increased antioxidant activity …
against the adverse effects of neomycin by using the zebrafish lateral line. The zebrafish
were administered the supplement drugs 1 h before neomycin exposure. One hour later,
animals were fixed in paraformaldehyde. Dose-response curves were generated to evaluate
the protective effect on hair cells. The screen identified 3 supplements (quercetin, catechin
and tannic acid). Three minutes after exposure to neomycin, increased antioxidant activity …