In vivo Treg suppression assays
Regulatory T cells: Methods and Protocols, 2011•Springer
To fully examine the functionality of a regulatory T cell (T reg) population, one needs to
assess their ability to suppress in a variety of in vivo models. We describe five in vivo models
that examine the suppressive capacity of T regs upon different target cell types. The
advantages and disadvantages of each model including resources, time, and technical
expertise required to execute each model are also described.
assess their ability to suppress in a variety of in vivo models. We describe five in vivo models
that examine the suppressive capacity of T regs upon different target cell types. The
advantages and disadvantages of each model including resources, time, and technical
expertise required to execute each model are also described.
Abstract
To fully examine the functionality of a regulatory T cell (Treg) population, one needs to assess their ability to suppress in a variety of in vivo models. We describe five in vivo models that examine the suppressive capacity of Tregs upon different target cell types. The advantages and disadvantages of each model including resources, time, and technical expertise required to execute each model are also described.
Springer