Synthetic peptides of human papillomavirus type 18 E6 harboring HLA-A2. 1 motif can induce peptide-specific cytotoxic T-cells from peripheral blood mononuclear …
H Yoon, MK Chung, SS Min, HG Lee, WD Yoo… - Virus research, 1998 - Elsevier
To identify cytotoxic T-cell (CTL) epitopes against human papillomavirus type 18 (HPV 18)
E6 protein that might be useful for developing peptide-based vaccine against HPV 18
infection, 18 peptides which possibly contain CTL epitopes were selected on the basis of
previously described human leukocyte antigen (HLA)-A2. 1-binding motif and chemically
synthesized. In the binding assay of the synthetic peptides, 8 out of 18 synthetic peptides
enhanced the expression of HLA-A2. 1 molecules on T2 cell surface, which implies that …
E6 protein that might be useful for developing peptide-based vaccine against HPV 18
infection, 18 peptides which possibly contain CTL epitopes were selected on the basis of
previously described human leukocyte antigen (HLA)-A2. 1-binding motif and chemically
synthesized. In the binding assay of the synthetic peptides, 8 out of 18 synthetic peptides
enhanced the expression of HLA-A2. 1 molecules on T2 cell surface, which implies that …
