Regulation of an inflammatory disease: Krüppel-like factors and atherosclerosis

MK Jain, P Sangwung, A Hamik - Arteriosclerosis, thrombosis, and …, 2014 - ahajournals.org
Arteriosclerosis, thrombosis, and vascular biology, 2014ahajournals.org
This invited review summarizes work presented in the Russell Ross lecture delivered at the
2012 proceedings of the American Heart Association. We begin with a brief overview of the
structural, cellular, and molecular biology of Krüppel-like factors. We then focus on
discoveries during the past decade, implicating Krüppel-like factors as key determinants of
vascular cell function in atherosclerotic vascular disease.
This invited review summarizes work presented in the Russell Ross lecture delivered at the 2012 proceedings of the American Heart Association. We begin with a brief overview of the structural, cellular, and molecular biology of Krüppel-like factors. We then focus on discoveries during the past decade, implicating Krüppel-like factors as key determinants of vascular cell function in atherosclerotic vascular disease.
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