(1→ 3)-β-D-glucan levels correlate with neurocognitive functioning in HIV-infected persons on suppressive antiretroviral therapy: a cohort study
M Hoenigl, MF de Oliveira, J Pérez-Santiago, Y Zhang… - Medicine, 2016 - journals.lww.com
Medicine, 2016•journals.lww.com
Microbial translocation from the gut is associated with immune dysfunction, persistent
inflammation, and likely plays a role in the pathogenesis of neurocognitive dysfunction
during HIV infection.(1→ 3)-β-D-Glucan (BDG) is a component of most fungal cell walls and
might be a useful indicator of gut mucosal barrier impairment. The objective of this study was
to evaluate whether higher blood BDG levels correlate with impaired neurocognitive
functioning in a cohort of HIV-infected adults with suppressed levels of HIV RNA in blood …
inflammation, and likely plays a role in the pathogenesis of neurocognitive dysfunction
during HIV infection.(1→ 3)-β-D-Glucan (BDG) is a component of most fungal cell walls and
might be a useful indicator of gut mucosal barrier impairment. The objective of this study was
to evaluate whether higher blood BDG levels correlate with impaired neurocognitive
functioning in a cohort of HIV-infected adults with suppressed levels of HIV RNA in blood …
Abstract
Microbial translocation from the gut is associated with immune dysfunction, persistent inflammation, and likely plays a role in the pathogenesis of neurocognitive dysfunction during HIV infection.(1→ 3)-β-D-Glucan (BDG) is a component of most fungal cell walls and might be a useful indicator of gut mucosal barrier impairment. The objective of this study was to evaluate whether higher blood BDG levels correlate with impaired neurocognitive functioning in a cohort of HIV-infected adults with suppressed levels of HIV RNA in blood plasma.
Lippincott Williams & Wilkins