Initiation of antiretroviral therapy in early asymptomatic HIV infection.

JD Lundgren, AG Babiker, F Gordin… - The New England …, 2015 - europepmc.org
Background Data from randomized trials are lacking on the benefits and risks of initiating
antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV)
infection who have a CD4+ count of more than 350 cells per cubic millimeter. Methods We
randomly assigned HIV-positive adults who had a CD4+ count of more than 500 cells per
cubic millimeter to start antiretroviral therapy immediately (immediate-initiation group) or to
defer it until the CD4+ count decreased to 350 cells per cubic millimeter or until the …

[HTML][HTML] Initiation of antiretroviral therapy in early asymptomatic HIV infection

Insight Start Study Group - New England Journal of Medicine, 2015 - Mass Medical Soc
Background Data from randomized trials are lacking on the benefits and risks of initiating
antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV)
infection who have a CD4+ count of more than 350 cells per cubic millimeter. Methods We
randomly assigned HIV-positive adults who had a CD4+ count of more than 500 cells per
cubic millimeter to start antiretroviral therapy immediately (immediate-initiation group) or to
defer it until the CD4+ count decreased to 350 cells per cubic millimeter or until the …