Immune activation and HIV persistence: considerations for novel therapeutic interventions
H Hatano - Current Opinion in HIV and AIDS, 2013 - journals.lww.com
H Hatano
Current Opinion in HIV and AIDS, 2013•journals.lww.comThere appears to be a clear and consistent relationship between immune activation and
viral persistence in treated HIV disease. Whether this relationship is causal or mediated
through other mechanisms is still unknown. Small-scale, pathogenesis-oriented
interventional studies are necessary to further evaluate this relationship and the effect of
potential interventions.
viral persistence in treated HIV disease. Whether this relationship is causal or mediated
through other mechanisms is still unknown. Small-scale, pathogenesis-oriented
interventional studies are necessary to further evaluate this relationship and the effect of
potential interventions.
Summary
There appears to be a clear and consistent relationship between immune activation and viral persistence in treated HIV disease. Whether this relationship is causal or mediated through other mechanisms is still unknown. Small-scale, pathogenesis-oriented interventional studies are necessary to further evaluate this relationship and the effect of potential interventions.
Lippincott Williams & Wilkins