A reappraisal of the MECT1/MAML2 translocation in salivary mucoepidermoid carcinomas

RR Seethala, S Dacic, K Cieply, LM Kelly… - The American journal …, 2010 - journals.lww.com
The MECT1/MAML2 translocation is identified in a large proportion of mucoepidermoid
carcinomas (MEC) of the salivary gland and is an emerging favorable prognosticator.
However, there are conflicting data on this translocation's specificity, restriction to
low/intermediate MEC, and strength as a prognosticator. We present our experience with the
MECT1/MAML2 translocation in a large cohort of MECs to address these issues. We
analyzed 55 salivary MEC and 36 potential MEC mimics (24 Warthin tumors, 5 …