Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: a meta-analysis

JAC Sterne, S Murthy, JV Diaz, AS Slutsky, J Villar… - Jama, 2020 - jamanetwork.com
Importance Effective therapies for patients with coronavirus disease 2019 (COVID-19) are
needed, and clinical trial data have demonstrated that low-dose dexamethasone reduced
mortality in hospitalized patients with COVID-19 who required respiratory support. Objective
To estimate the association between administration of corticosteroids compared with usual
care or placebo and 28-day all-cause mortality. Design, Setting, and Participants
Prospective meta-analysis that pooled data from 7 randomized clinical trials that evaluated …