Mechanisms for the resolution of organ fibrosis
JC Horowitz, VJ Thannickal - Physiology, 2019 - journals.physiology.org
Physiology, 2019•journals.physiology.org
Fibrosis is a dynamic process with the potential for reversibility and restoration of near-
normal tissue architecture and organ function. Herein, we review mechanisms for resolution
of organ fibrosis, in particular that involving the lung, with an emphasis on the critical roles of
myofibroblast apoptosis and clearance of deposited matrix.
normal tissue architecture and organ function. Herein, we review mechanisms for resolution
of organ fibrosis, in particular that involving the lung, with an emphasis on the critical roles of
myofibroblast apoptosis and clearance of deposited matrix.
Fibrosis is a dynamic process with the potential for reversibility and restoration of near-normal tissue architecture and organ function. Herein, we review mechanisms for resolution of organ fibrosis, in particular that involving the lung, with an emphasis on the critical roles of myofibroblast apoptosis and clearance of deposited matrix.
American Physiological Society