Background The diagnosis of food allergy (FA) can be challenging because approximately
half of food-sensitized patients are asymptomatic. Current diagnostic tests are excellent
makers of sensitization but poor predictors of clinical reactivity. Thus oral food challenges
(OFCs) are required to determine a patient's risk of reactivity. Objective We sought to
discover genomic biomarkers of clinical FA with utility for predicting food challenge
outcomes. Methods Genome-wide DNA methylation (DNAm) profiling was performed on …