A protein interaction network associated with asthma

S Hwang, SW Son, SC Kim, YJ Kim, H Jeong… - Journal of theoretical …, 2008 - Elsevier
Identifying candidate genes related to complex diseases or traits and mapping their
relationships require a system-level analysis at a cellular scale. The objective of the present
study is to systematically analyze the complex effects of interrelated genes and provide a
framework for revealing their relationships in association with a specific disease (asthma in
this case). We observed that protein–protein interaction (PPI) networks associated with
asthma have a power-law connectivity distribution as many other biological networks have …