An association between IL-9 and IL-9 receptor gene polymorphisms and atopic dermatitis in a Korean population

JH Namkung, JE Lee, E Kim, GT Park, HS Yang… - Journal of …, 2011 - Elsevier
BACKGROUND: The genes encoding IL-9 and IL-9R have recently been implicated in the
genetic basis of asthma and allergy. Although studies performed on transgenic and
knockout mice have shown conflicting results, no evidence of skin changes has ever been
reported in these animals. OBJECTIVE: To find association of the SNPs in IL-9 and IL-9R
genes and interaction of these genes in atopic dermatitis. METHOD: We genotyped 5 SNPs
from the IL-9 and IL-9R genes of 1090 subject samples (631 AD patients and 459 normal …