Neonatal 3, 4-methylenedioxymethamphetamine (ecstasy) alters dopamine and serotonin neurochemistry and increases brain-derived neurotrophic factor in the …
JB Koprich, NG Campbell, JW Lipton - Developmental brain research, 2003 - Elsevier
Growing concerns surround the risk of fetal exposure to 3, 4-
methylenedioxymethamphetamine (MDMA; ecstasy). Prior animal studies using neonatal
rats administered MDMA from postnatal days (P) 11–20 (a period approximating third
trimester brain development in humans) have demonstrated long-lasting decrements in
serotonin (5-HT) and learning; however, no studies have examined the acute post-MDMA
response of the brain at this early age. Specifically, it is of interest whether MDMA …
methylenedioxymethamphetamine (MDMA; ecstasy). Prior animal studies using neonatal
rats administered MDMA from postnatal days (P) 11–20 (a period approximating third
trimester brain development in humans) have demonstrated long-lasting decrements in
serotonin (5-HT) and learning; however, no studies have examined the acute post-MDMA
response of the brain at this early age. Specifically, it is of interest whether MDMA …