Protective effect of calcium channel blocker verapamil on morphological and functional state of hair cells of the organ of Corti in experimental kanamycin-induced …
SG Zhuravskii, AI Lopotko, VV Tomson… - Bulletin of experimental …, 2002 - Springer
SG Zhuravskii, AI Lopotko, VV Tomson, AG Ivanov, AN Chomskii, KV Nurskii
Bulletin of experimental biology and medicine, 2002•SpringerThe protective effect of verapamil against acute ototoxic sensorineural damage produced by
intraperitoneal injections of kanamycin (50 mg/kg daily for 14 day) was studied on rats. The
functional (otoacoustic emission), histological, and physiological methods proved the
protective effect of daily injections of calcium channel blocker verapamil (2 mg/kg) on the
state of hair cells of the organ of Corti.
intraperitoneal injections of kanamycin (50 mg/kg daily for 14 day) was studied on rats. The
functional (otoacoustic emission), histological, and physiological methods proved the
protective effect of daily injections of calcium channel blocker verapamil (2 mg/kg) on the
state of hair cells of the organ of Corti.
Abstract
The protective effect of verapamil against acute ototoxic sensorineural damage produced by intraperitoneal injections of kanamycin (50 mg/kg daily for 14 day) was studied on rats. The functional (otoacoustic emission), histological, and physiological methods proved the protective effect of daily injections of calcium channel blocker verapamil (2 mg/kg) on the state of hair cells of the organ of Corti.
Springer
