Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular
mechanisms involved in the regulation of conventional outflow resistance and thus
intraocular pressure; and their dysfunction resulting in ocular hypertension. In this review,
we describe the standard procedures used for the isolation of TM cells from several animal
species including humans, and the methods used to validate their identity. Having a set of
standard practices for TM cells will increase the scientific rigor when used as a model, and …