IL-33 impacts on the skin barrier by downregulating the expression of filaggrin
J Seltmann, LM Roesner, FW von Hesler… - Journal of Allergy and …, 2015 - jacionline.org
In the first approach, monolayer keratinocytes and skin samples were stimulated with IL-33
or IL-4 to analyze FLG mRNA expression (see additional information in the Methods section
in this article's Online Repository at www. jacionline. org). We confirmed the effect of IL-4 on
FLG in Ca21-differentiated human primary keratinocytes (Fig 1, A). On investigating
or IL-4 to analyze FLG mRNA expression (see additional information in the Methods section
in this article's Online Repository at www. jacionline. org). We confirmed the effect of IL-4 on
FLG in Ca21-differentiated human primary keratinocytes (Fig 1, A). On investigating
