Saturated and monounsaturated fatty acids are the most abundant fatty acidspecies in
mammalian organisms, and their distribution is regulated bystearoyl-CoA desaturase, the
enzyme that converts saturated intomonounsaturated fatty acids. A positive correlation
between highmonounsaturated fatty acid levels and neoplastic transformation has
beenreported, but little is still known about the regulation of stearoyl-CoAdesaturase in cell
proliferation and apoptosis, as well as in cancerdevelopment. Here we report that simian …