In VivoQuantitation of cerebral metabolite concentrations using natural abundance13C MRS at 1.5 T
S Blüml - Journal of Magnetic Resonance, 1999 - Elsevier
A method for the quantitation of cerebral metabolites on a clinical MR scanner by natural
abundance13C MRSin vivois described. Proton-decoupled spectra were acquired with a
power deposition within FDA guidelines using a novel coil design. myo-Inositol, quantified
by a separate proton MRS, and readily detectable in13C MRS, was used as an internal
reference. Normal concentrations, measured in four control subjects, age 7 months to 12
years, were glutamate 9.9±0.7, glutamine 5.6±1.0, and NAA 8.8±2.8 mmol/kg. In a patient …
abundance13C MRSin vivois described. Proton-decoupled spectra were acquired with a
power deposition within FDA guidelines using a novel coil design. myo-Inositol, quantified
by a separate proton MRS, and readily detectable in13C MRS, was used as an internal
reference. Normal concentrations, measured in four control subjects, age 7 months to 12
years, were glutamate 9.9±0.7, glutamine 5.6±1.0, and NAA 8.8±2.8 mmol/kg. In a patient …