Convalescent plasma to treat COVID-19: possibilities and challenges

JD Roback, J Guarner - Jama, 2020 - jamanetwork.com
In this issue of JAMA, Shen et al report findings from a preliminary study of 5 severely ill
patients with coronavirus disease 2019 (COVID-19) who were treated in the Shenzhen Third
People's Hospital, China, using plasma from recovered individuals. 1 All patients had severe
respiratory failure and were receiving mechanical ventilation; 1 needed extracorporeal
membrane oxygenation (ECMO) and 2 had bacterial and/or fungal pneumonia. Four
patients without coexisting diseases received convalescent plasma around hospital day 20 …