Adenoviral-Mediated Overexpression of the NA, K-ATPase β1 Subunit Gene Increases Lung Edema Clearance and Improves Survival During Acute Hyperoxic Lung …
P Factor, V Dumasius, F Saldias, JI Sznajder - Chest, 1999 - journal.chestnet.org
Rats exposed to acute hyperoxia develop a lung injury characterized by pulmonary edema
and decreased ability to clear lung liquid. 1, 2 Accumulating evidence indicates that active
Na transport is an important contributor to lung edema clearance. 3–5 In the alveolus, Na, K-
adenosine triphosphatases (ATPases) have been shown to be responsible for active Na
transport across the alveolar epithelium. 3, 5, 6 These pumps works in concert with other
epithelial transport proteins, including water and apical Na channels, to generate a …
and decreased ability to clear lung liquid. 1, 2 Accumulating evidence indicates that active
Na transport is an important contributor to lung edema clearance. 3–5 In the alveolus, Na, K-
adenosine triphosphatases (ATPases) have been shown to be responsible for active Na
transport across the alveolar epithelium. 3, 5, 6 These pumps works in concert with other
epithelial transport proteins, including water and apical Na channels, to generate a …
